Beyett Lab

We are a molecular pharmacology lab primarily focused on kinases and phosphatases in cancer signaling. We utilize structural biology to understand molecular mechanisms of oncogenic activation and drug resistance and use this information to guide the development of novel chemical probes and inhibitors. We rely on high-throughput screening to identify lead molecules and rationally optimize them through structure-based drug design. These molecules serve as valuable tools for the validation of new drug targets, better study of pathophysiology, and exploration of novel therapeutic strategies. Our goal is to provide a foundation for the development of next-generation cancer therapeutics.